Pain and swelling of the big toe joint can often be seen clinically. First of all, ask about the medical history to determine whether the patient has suffered from toe fracture, tendon, muscle injury, etc. Secondly, inflammation of some joints, such as degenerative arthritis, rheumatoid arthritis and ankylosing spondylitis, can also cause pain in this part. Of course, some special diseases of metatarsophalangeal joints, such as gout and hallux valgus, will cause swelling and pain in this part. There are also some patients because of lumbar intervertebral disc protrusion, especially if the protrusion to the first segment compresses the nerve root, resulting in pain at the segment of the foot it controls. Finally, we should also consider whether there are some space occupying lesions, benign or malignant tumors, and the pain caused by the growth and compression of surrounding tissues, so the pain will be accompanied by redness and swelling or some other changes, and we should go to the hospital in time.