Rheumatoid arthritis is caused by the immune allergy caused by streptococcal infection, resulting in redness, swelling and pain of joints. Generally, it damages large joints, and may cause wandering joint pain. It is mainly treated with penicillin, generally large doses of penicillin combined with aspirin. Rheumatoid arthritis is a chronic autoimmune disease, which mainly involves small joints, and mainly symmetrical small joints, so joints may not appear obvious redness, swelling and pain. Rheumatoid arthritis is mainly treated with chronic chemosynthetic drugs. Non steroidal anti-inflammatory drugs can also be added when acute joint pain occurs. Generally, it is only used for a short time. In the long run, it needs to be treated with chemosynthetic drugs, such as methotrypia, tripterygium glycosides, leflunomide, and so on.