Good question! For example, take dragons. Common staple of fantasy (and on occasion science fiction). Dragons have the particular case of having fire breath, making them kind of overpowered evolutionarily (conveniently, fire breath is such a complex system that it would never evolve naturally, so we can discount it). Still, they’re an example of a species that can show intelligence but is quadrupedal without limbs specifically devoted to “grab” and “hold” and “write” and “use tool” like humans.
The issue I think isn’t necessarily that species like these can’t use tools, it’s just getting to the point where they choose to. Using your front legs to manipulate objects in the world is a big step up from using the claws at the end of them to stab prey, but mechanically it isn’t difficult to do. A dragon (or other token quadrupedal species) could simply stand on its hind legs, using a tail for balance if it has one, and then the front legs are free to use tools, build complex things, and type angry comments into computers.
The impetus to actually build tools would probably come from a place of having already dominated the ecosystem and no longer needing to use the front legs as heavily for attack. A dragon, sufficiently intelligent, will find that they are already an apex predator, and will learn to use their front legs for something other than attacking prey which they can already do very efficiently. Non-apex predators might still develop this, like we humans did (against any other animal, we lose, but we are bipedal and can built sharp pointy things), as a way to evade and even attack predators.
So it’s mechanically possible. Then, all we need to do is build gradually more-advanced tools with our current set, and bam! Modern era!
The issue with being quadrupedal is that you don’t have arms to carry stuff with. Then again, it’s still not impossible to carry things around with you: a dragon species could make simple vests with which to carry tools, or need be, simply walk on their hind legs with their tails for balance.
Besides, once you get to the technologically-“advanced” era (i.e. tech level of 1000 B.C.E.), members of your society will probably be smart enough to build tools to carry tools, and by then, we’re out of the developing-complex-tools phase and into the expanding-to-become-the-dominant-species phase.
Ultimately, it’s probably just as easy for quadrupeds to develop tools as for bipeds. Supply impetus to do so, and a species will find a way - no matter how many legs.