What is the cause of prostatic cyst Prostate cysts can be complicated by infection and stones. Larger cysts can compress the urethra and cause difficulty in urination. Common symptoms include urgency of urination, frequency of urination, difficulty in urination, thin urine line, and retention of urine. Congenital prostatic cysts are often associated with congenital diseases such as hypospadias, cryptorchidism, and renal agenesis