Organic factors of premature ejaculation in men Which one is good in Weifang Chang'an Hospital? Organic factors causing premature ejaculation: 1. The glans sensitivity is too high: under normal circumstances, the cavernous nerve of the penis is distributed in the coronal groove of the glans, resulting in a relatively high sensitivity to sexual nerve stimulation. As long as the penis is inserted into the vagina or even just touches the vaginal orifice, ejaculation will be too fast, that is, premature ejaculation