What are the best Chinese patent medicines for liver cirrhosis
There are many traditional Chinese medicines used in clinical treatment of liver cirrhosis, among which the most commonly used ones are: invigorating qi and strengthening spleen, such as atractylodes macrocephala, poria cocos, astragalus membranaceus, codonopsis pilosula, etc; Yin nourishing, such as Asparagus, Ophiopogon japonicus, ginseng, wolfberry, rehmannia glutinosa, etc; Soothing the liver and regulating qi, such as Fructus Aurantii, Radix Bupleuri, Aucklandiae, Rhizoma Cyperi, Melia azedarach, Bergamot, and Bark of Abdomen; Activating blood circulation and removing silt, such as salvia miltiorrhiza, peach kernel, safflower, and ground turtle worm; Soft, hard and loose, such as turtle shell, cannon beetle, raw oyster, etc.
What drugs are commonly used to treat cirrhosis?
In clinical practice, the traditional Chinese medicine for liver cirrhosis includes Anluo Huaxian Pill, Fuzheng Huayu Capsule, Compound Biejia Ruangan Tablet, etc. During this period, patients can also take antiviral drugs, such as interferon, enteka, etc. It is suggested that patients should avoid excessive drinking, maintain good living habits and eating habits, balance their meals, control their weight, and not often eat too greasy food.
Drug treatment of liver cirrhosis
1. Interferon (IFN)
Interferon for chronic hepatitis B. It is mainly interferon a. Interferon a has been used to treat chronic hepatitis B for more than 20 years, and there is basically consensus:
(1) Interferon a is an effective drug in the treatment of chronic hepatitis b, but the efficacy is not satisfactory. Persistent effective rate (refer to 1 year follow-up after drug withdrawal; negative conversion rate of serum HBV-DNA and HbeAg is about 20%~40%).
(2) The anti HBV effect of interferon a is mainly to inhibit HBV replication, which is manifested by the negative conversion of serum HBeAg and HBV DNA, and it is difficult to clear HBV. Therefore, the recurrence rate after treatment is high.
(3) The domestic experience is that there is no difference in the efficacy of various interferons. The efficacy of domestic and imported interferons, a2a and a2b are similar, which can be selected according to the patient's economic affordability.
(4) IFN treatment has some side effects, such as flu like symptoms in the early stage, fatigue, depression, bone marrow depression and some autoimmune diseases in the later stage. IFN treatment is expensive and its use is limited.
2. Nucleoside analog
Top 10 drugs for liver cirrhosis Name of drugs for liver cirrhosis
Nucleoside analogues have become a hot topic in the field of antiviral drug research due to their strong antiviral effect, less adverse reactions, oral administration, convenient use, simple chemical structure and artificial synthesis. It has obvious inhibitory effect on HIV, HBV, HCV, measles virus, etc. New nucleoside analogues for anti HBV, mainly lamivudine (officially marketed), famciclovir (phase III clinical trial), lobucavir, adeforir and FTC (two membrane oxyfluorothiothymidine) are all in phase clinical trials. FMAU (fluorouracil arabinose) and FDDC (oxydideoxythymidine) are undergoing Phase I clinical trials. BMS200475 (epoxy hydroxycarbodeoxyguanosine) is undergoing preclinical study.
3. Immunomodulator
BaYiYiTai; Human fetal hepatocyte growth factor; Thymosin al; Nucleic acid vaccine; Adoptive cellular immunity.
4. Combined medication
Antiviral drug combination therapy may improve the efficacy. The commonly used combination treatment uses interferon a combined with immunomodulators, such as thymosin al, thymosin, levamisole coating agent, hepatitis B vaccine, etc. Interferon can also be used in combination with other antiviral drugs, such as lamivudine. However, the efficacy of combination therapy for chronic hepatitis B needs further scientific clinical verification.
Top 10 drugs for liver cirrhosis Name of drugs for liver cirrhosis
5. Comprehensive treatment
At present, there is no specific drug treatment, so it is not advisable to abuse drugs, or it will increase the burden on the liver. It can only be through some auxiliary treatment methods:
① Multivitamin C, E, and B supplementation can improve liver cell metabolism, prevent or reduce steatosis, and protect cells. Vitamin K, B12 and folic acid can also be supplemented as appropriate.
② Inosine, a drug that protects hepatocytes, is a cell activator that can increase the level of adenosine triphosphate and can be converted into other nucleotides.
③ U3000, an enzyme reducing and yellowing reducing drug, has a wide variety, with little difference in efficacy. Biphenyl diester, glycyrrhizin or glycyrrhizin, potassium aspartate, ursodeoxycholic acid and traditional Chinese medicine preparations containing Schisandra chinensis, Sedum sarmentosum, Silymarin and other ingredients can be selected.
④ The most effective way to improve plasma albumin u3000 is albumin infusion. The half-life of albumin is 17-21 days, and attention should be paid to the dosage and interval in clinical use. If it is used 1-2 times a week, it is difficult to improve the albumin level of patients. During the treatment with albumin, fresh plasma can be used alternately. There have been reports of using Wuji Baifeng Pill, Compound Angelica Tablets and other methods in the past, but in clinical use, the effect is not obvious.
⑤ Methylphenidate can improve the symptoms of moderate and severe chronic fatigue in patients with post hepatitis cirrhosis. Oral methylphenidate 10-20mg daily, once or twice a day, and discontinue the drug for two days after five consecutive days. The median treatment time was 6 months.
What medicine does cirrhosis take?
Chinese patent medicine "Qishen Yanggan Capsule" and other two kinds) are treated with pure Chinese medicine. Select medication according to the needs of the patient's condition. 30 days is a course of treatment, and 120 days is a stage. Patients with early cirrhosis should be reexamined once in a stage. One month or two month examination items for patients with advanced cirrhosis are determined according to the condition. After eight months or one year of treatment, a comprehensive review and control shall be conducted.
What drug does cirrhosis use?
Generally, vitamin drugs, antiviral drugs, liver protection drugs, beta blockers, etc. can be used to treat liver cirrhosis, but the dosage should follow the doctor's advice.
1. Vitamin medicine: patients with liver cirrhosis can take vitamin medicine according to the doctor's advice, such as vitamin B, which can protect liver cells, prevent fatty liver, and promote liver cell regeneration. At the same time, vitamin C and vitamin E can also be used according to the doctor's advice to avoid the oxidation of liver cells caused by harmful substances, which can also protect the liver to a certain extent.
Top 10 drugs for liver cirrhosis Name of drugs for liver cirrhosis
2. Antiviral drugs: entecavir is mainly used to treat liver cirrhosis caused by hepatitis, but it has adverse reactions such as gastrointestinal reactions, dizziness, lethargy, etc. At the same time, SOPHOBUVIVIPALTAVIR Tablets are also antiviral drugs, mainly used to treat hepatitis C cirrhosis.
3. Liver protection drug: the commonly used drug is compound glycyrrhizin, which is a liver protection drug that can be taken by patients with cirrhosis, but it is easy to cause hypokalemia. It is recommended to take it under the guidance of the doctor, and adjust the dosage according to the condition to prevent adverse reactions.
4. Beta blocker: The commonly used drug is metoprolol, which can treat portal hypertension caused by cirrhosis according to the doctor's advice, but may lead to hypotension, abnormal liver function and abnormal respiratory system.
What to take for cirrhosis
Cirrhotic patients are more sensitive to drugs. They can choose anti fibrosis drugs, anti enzyme and anti jaundice drugs, vitamins, metabolism promoting drugs, liver protection and repair drugs, nutritional support drugs, and metabolism promoting drugs according to the specific conditions of the patients. The liver metabolism of patients with advanced cirrhosis is abnormal, so they can take drugs to promote metabolism, which can theoretically supply the energy demand of the body, such as adenosine triphosphate, coenzyme A, etc. Vitamin drugs can protect the liver, participate in the metabolism of the body, and maintain cell function. Yeast tablets and vitamin B complex preparations are commonly used. Enzyme lowering and jaundice reducing drugs: Qianglining, potassium magnesium aspartate, salvia miltiorrhiza injection, smetai and other drugs can reduce transaminase in patients with cirrhosis and promote jaundice regression. Nutritional support drugs: human serum albumin, fresh plasma, fat emulsion, energy mixture and other drugs, which have a good role in protecting the liver and supplementing nutrition. Anti fibrosis drugs. Liver fibrosis is the pathological process of liver disease developing into cirrhosis. Colchicine, interferon, penicillamine, etc. have anti fibrosis effects. Liver protection and repair drugs: silybin and inosine are commonly used liver protection and repair drugs. Silybin has the effect of protecting liver cell membrane and resisting various liver toxins, and inosine can promote the recovery of damaged liver cells. At present, there are many kinds of liver protection drugs on the market. If the liver function is normal, it is generally inappropriate to take liver protection drugs. If the liver function is abnormal, you can choose one or two kinds of liver protection, enzyme reduction, and yellowness reduction drugs. When taking these drugs, it is best for patients to use them reasonably under the guidance of doctors. Do not blindly follow the crowd. Liver fibrosis is the pathological basis of liver cirrhosis. Early cirrhosis often has active liver fiber proliferation, and the relevant indicators are significantly increased. Therefore, anti fibrosis treatment is of great significance to prevent the occurrence and development of early cirrhosis. The principle of medication is to target the cause and use drugs reasonably.
Which drugs are better for the treatment of early cirrhosis
Liver cirrhosis is a chronic disease that affects the whole body, mainly including extensive destruction, degeneration, necrosis and regeneration of liver parenchymal cells, proliferation of fibrous tissue, and normal liver structure disorder. Due to the contraction of the scar, the inverted liver becomes hard and forms cirrhosis. Cirrhosis itself is not terrible, but its complications directly threaten the lives of patients. Therefore, patients with early cirrhosis must be actively treated. So what are the drugs for the treatment of early cirrhosis? In China, the main treatment for early cirrhosis is drug therapy. However, it should be clear that the drugs for the treatment of liver cirrhosis are mainly aimed at various complications, such as upper gastrointestinal bleeding, hepatic encephalopathy, ascites, electrolyte acid-base imbalance, etc. Clinically, cirrhosis is mostly post hepatitis B cirrhosis, so antiviral treatment is mainly aimed at hepatitis B virus. The antiviral drugs used by cirrhosis patients are mostly nucleoside analogues, such as lamivudine, entecavir, adefovir, etc. Recommendation: What are the symptoms of cirrhosis? Finally, experts pointed out that antiviral drugs can only slow down the destruction of the liver, but can not reverse cirrhosis. If you want to reverse early cirrhosis, you should actively treat symptomatically. For patients with hepatitis B, the latest treatment method of hepatitis B can be used. This therapy is the best treatment method for viral hepatitis (such as hepatitis A, hepatitis B, hepatitis C, etc.) at present. This therapy has a very strong immune killing effect, can effectively activate the immune system of the body, and produce various immune cells that kill hepatitis virus; At the same time, the use of ozone therapy apparatus to produce oxygen and its active metabolites to induce the human body to produce cytotoxic T lymphocytes and natural killer cells (NK), use the human body's own immune function to attack and eliminate hepatitis virus, and avoid the drawback of traditional antiviral drugs rebounding after drug withdrawal. Recommendation: What are the symptoms of early liver cirrhosis caused by hepatitis B? Zhengzhou Liver Hospital is a leading and first-class key Zhengzhou liver disease treatment hospital in China. It has been rated as "Baixin reassuring demonstration hospital" and "key specialized hospital of liver disease" by the ministry, provincial and municipal health departments, The hospital has helped tens of thousands of patients to relieve the pain of disease, so that the liver of patients will never be injured again! If you have hepatitis B, please come to Zhengzhou Liver Hospital. We will help you get rid of the disease and recover your health as soon as possible!
