Beyond 100 years old

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• In fact, I think we know more about Alzheimer's disease prevention than about cancer prevention. Our main tool to prevent cancer is not to smoke and keep our metabolism healthy, but this is a rough line treatment, which can only let us go so far. We still need to actively carry out screening and hope to somehow try to find any cancer that does exist before it is too late. For Alzheimer's disease, we have a larger prevention kit to use, and there are better diagnostic methods. If we observe carefully, it is relatively easy to find cognitive decline in the early stage. We are also learning more about genetic factors, including those that can at least partially offset high-risk genes such as APOE e4. Since metabolism plays such an important role in high-risk 4 patients like Stephanie, our first step is to solve some of their possible metabolic problems. Our goal is to improve glucose metabolism, inflammation and oxidative stress. For people like her, a possible suggestion is to turn to a mediterranean style diet. In addition to regular consumption of fatty fish, they should also eat more monounsaturated fat and less refined carbohydrates. There is evidence that supplementation of o-3 fatty acid DHA (contained in fish oil) may help maintain brain health, especially for e4/e4 gene carriers. Due to metabolic changes and blood brain barrier dysfunction caused by 4, higher doses of DHA may be required. This is also an area where ketogenic diet may provide real functional advantages. When a person is in a ketosis state, their brain relies on the mixture of ketones and glucose as fuel. Research on Alzheimer's disease patients found that although their brain's ability to use glucose became worse, their ability to metabolize ketones did not decline. Therefore, it may be meaningful to try to diversify the fuel sources of the brain from single glucose to glucose and ketone. A systematic review of randomized controlled trials found that ketogenic therapy can improve the general cognition and memory of patients with mild cognitive impairment and early Alzheimer's disease, which can be regarded as an iex fuel strategy. In Stephanie's case, she not only gave up adding sugar and highly refined carbohydrates, but also gave up alcohol. Alcohol is really ( View original text )

  unicorn 11 likes 2024-01-25 12:58:37

• In his later years, Richard Overton liked to drink a small glass of bourbon at his home in Austin, Texas, and then smoke some Tampa Sweets with the gas stove to pass the time. He insisted that he would never take a big puff of cigars, a wise man needless to say. As we all know, Mr. Overton was born during the administration of Theodore Roosevelt and died at the end of 2018 at the age of 112. Not to be outdone, Henry Allingham, a British World War I veteran, attributed his 113 year life span to "cigarettes, whiskey and wild women". It's a pity that he has never met Jeanne Calment, a French adventurous woman. She once joked: "I only have one wrinkle, and I am sitting on it." She has been riding a bicycle until she was 100 years old, and kept the habit of smoking until she was 117 years old. Maybe she should not quit smoking, because she died five years later at the age of 122, becoming the oldest person ever. ( View original text )

  unicorn 8 likes 2024-01-24 13:12:51

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