【 Building materials network 】On Bisphenol A In the case of disputes over the impact on human health, Professor Ning Guang's team from the Department of Endocrinology, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine has provided a basis for the correlation between BPA and human endocrine metabolic diseases through a large sample of population studies. The results show that high levels of bisphenol A exposure will increase the risk of metabolic diseases such as obesity, type 2 diabetes, low albuminuria and thyroid dysfunction. Therefore, experts remind that plastic water should be minimized cup To avoid microwave Lunch box Heating of, use instead Glassware 。

Higher bisphenol A exposure or increased risk of obesity and diabetes

Animal studies have found that a certain dose of bisphenol A has the effect of simulating estrogen after entering the body, which can affect sexual development, nervous system development, glucose and lipid metabolism, especially in infants with incomplete organ development. However, at present, there are very few large sample population studies, and only a few studies have inconsistent results. The research team led by Professor Ning Guang, Department of Endocrine and Metabolic Diseases, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, explored the correlation between the exposure level of bisphenol A and type 2 diabetes in Chinese adults through a large sample population study. The study selected 3423 community residents over 40 years old in Shanghai community as the survey objects. The patients with type 2 diabetes mellitus were definitely diagnosed through oral glucose tolerance test and medical history, and the urine bisphenol A levels of all the study objects were measured.

Research shows that 87.7% of Chinese people over 40 years old can detect BPA in urine, with an average level of 0.81ng/mL. The study found that the risk of type 2 diabetes mellitus was significantly increased by 37% in those with high levels of bisphenol A exposure, and no significant correlation was found between those with low levels of bisphenol A exposure and the risk of type 2 diabetes mellitus. The results also showed that high levels of bisphenol A exposure increased the risk of systemic obesity by 50%, abdominal obesity by 28%, and insulin resistance by 37%. When human BPA exposure reaches a certain level, it may increase the risk of obesity and insulin resistance.

Risk of BPA high exposure or proteinuria, thyroid disease

The research team led by Professor Ning Guang also explored for the first time the correlation between the exposure level of bisphenol A and the risk of low-grade proteinuria in Chinese adults through the research of the same population. The results showed that the level of urinary bisphenol A was positively correlated with the risk of low-grade proteinuria in Chinese people over 40 years old. High exposure to bisphenol A may increase the risk of early cardiovascular disease risk factors, such as low-grade proteinuria, and the impact of bisphenol A exposure on proteinuria cannot be ignored.