Learning experience
2004-2009 Wuhan University School of Stomatology, Bachelor of Stomatology
2009-2012 Doctor, Department of Oral and Maxillofacial Surgery, School of Stomatology, Wuhan University
Work experience and position
2013-2014, post doctor, School of Chemistry and Molecular Science, Wuhan University
2014-2017, Postdoctoral candidate, Department of Biology, University of Pennsylvania, USA
2012-2014, attending physician, School of Stomatology, Wuhan University
2014-2015, Deputy Chief Physician, School of Stomatology, Wuhan University
2015-2018, Associate Chief Physician and Associate Professor, School of Stomatology, Wuhan University
2018-2019, Wuhan University School of Stomatology, chief physician and associate professor
2019 present, Chief Physician and Professor, School of Stomatology, Wuhan University
2020-2024, Deputy Director of Teaching Office, School of Stomatology, Wuhan University
2024-present, Vice President, School of Stomatology, Wuhan University
Research direction
Extracellular vesicles and tumor immunity
Awards and honors
"Zhu Yubi Medical Prize" of Wuhan University (2015)
Wuhan "Young and Middle aged Medical Backbone Talents Training Project" (2015)
China Association for Science and Technology "Youth Talent Promotion Project" (2016)
The second prize of the Natural Science Award of the Ministry of Education for Outstanding Achievements in Scientific Research in Colleges and Universities (ranking ninth, 2016)
National Science Fund for Distinguished Young Scholars (2019)
Hubei Outstanding Youth Fund (2020)
First Prize of Teaching Achievement Award of Hubei Higher Education Institutions (ranking fifth, 2023)
The 15th "Outstanding Youth of Wuhan University" (faculty, 2023)
The second prize of Hubei Province Technological Invention Award (ranking first, 2024)
Representative papers
one Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu ZL, Yang JG, Wang BK, Sun HH, Xia HF, Man QW, Zhong WQ, Antelo LF, Wu B, Xiong XP, Liu XM, Guan L, Li T, Liu SJ, Yang RF, Lu YT, Dong LY, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu YL, Kim JY, Chen YH, Dong HD, Zhao YF, Karakousis GC, Gangadhar TC, Schuchter LM, Herlyn M, Wherry EJ, Xu XW*, Guo W* （ two thousand and eighteen ） . Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 Response. Nature 560:382-386.
two Zhang LZ # , Yang JG # , Xia HF, Huang J, Liu HM, Wu M, Liu B, Wang WM*, Chen G* （ two thousand and twenty-three ） . PD-1 Carried on small extracellular vesicles leads to OSCC metastasis. J Dent Res 102:795-805.
three Xia HF # , Yu ZL # , Zhang LJ, Lin SL, Zhao Y, Huang J, Fu DD, Xie QH, Liu HM, Zhang ZL, Zhao YF, Wu M, Zhang W*, Pang DW*, Chen G* （ two thousand and twenty-three ） . Real-time dissection of the transportation and miRNA-release dynamics of small extracellular vesicles. Adv Sci 10:e2205566.
four Xiao BL # , Wang XL # , Xia HF, Zhang LZ, Wang KM, Chen ZK, Zhong YH, Jiang HG, Zhou FX, Wang W, Chen GL, Chen G* （ two thousand and twenty-three ） . HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy. Cancer Immunol Res 11:228-240.
five Yu ZL # , Liu XC # , Wu M, Shi S, Fu QY, Jia J*, Chen G* （ two thousand and twenty-two ） . Untouched isolation enables targeted functional analysis of tumour-cell-derived extracellular vesicles from tumour tissues. J Extracell Vesicles 11:e12214.
six Yu ZL # , Zhao Y # , Miao F, Wu M, Xia HF, Chen ZK, Liu HM, Zhao YF, Chen G* （ two thousand and twenty-one ） . In situ membrane biotinylation enables the direct labeling and accurate kinetic analysis of small extracellular vesicles in circulation. Anal Chem 93:10862-10870.
