What is the pharmacological effect of dopamine?
Dopamine is the precursor of norepinephrine, and its cardiovascular effect is dose dependent:
1. Small dose<2 μ g/(Kg. min) can excite dopamine receptor D1, so as to expand renal vessels, increase renal blood flow, and increase urine output.
2. The moderate dose of 2~10 μ g/(Kg. min) can increase the myocardial contractility, heart rate and cardiac output through the positive inotropic effect by exciting the beta receptor, while contracting the peripheral blood vessels, so as to maintain blood pressure and improve cardiac function.
3. When high dose dopamine is applied at 10-20 μ g/(Kg. min), it mainly activates α 1 receptor, which makes the arteries and veins of the appropriate circulation contract, increases the resistance of the whole blood vessels, and further presents microcirculatory disorders, which is adverse to heart failure.
4. The dose shall not exceed 20 μ g/(Kg. min).
So, what are the functions of dopamine?
Dopamine is a special substance in the body. It is a chemical substance used to help cells transmit signals. Dopamine is the most abundant neurotransmitter of catecholamine in the brain, helping to transmit nerve signals. Dopamine, a neurotransmitter, is closely related to people's emotions and feelings, and can transmit information about excitement and happiness.
In addition, dopamine may also be related to some of our addictive behaviors.
key word: Pharmacological effects of dopamine
What are the functions of dopamine
chemical substances
Neurotransmitter
