Original title: World Heart Day | New ideas for the treatment of cardiovascular problems!
Beijing, September 29 (Reporter Jiang Xiuping) The World Heart Alliance has set September 29 as World Heart Day since 1999. At present, cardiovascular and cerebrovascular diseases are one of the important causes of death for Chinese residents, which have become an important public health problem with high morbidity, high disability rate, high recurrence rate and high mortality. Recently, Professor Han Jingyan, head of the Department of Integrated Traditional Chinese and Western Medicine of Peking University Medical Department, and his team put forward new ideas for the treatment of cardiovascular and cerebrovascular problems at the first "Top Ten Academic Advances in Chinese Medicine in 2021" cutting-edge technology salon.
Han Jingyan made a detailed introduction to the scientific connotation of the theory of qi deficiency without fixation and qi supplement fixation based on the microvascular barrier. Starting with the damage of microvascular barrier, they revealed that the leakage of plasma albumin and liquid was related to the disorder of mitochondrial ATP synthase in vascular endothelial cells, the decrease of ATP content, the energy of assembling G-actin into F-actin, the low expression of gap linker protein between vascular endothelial cells, and the opening of gaps, which clarified the scientific connotation of qi deficiency without fixation. On this basis, the mechanism of Qishen Yiqi Dropping Pill, Shengmai Powder (Yiqi Fumai for Injection) and other compounds for invigorating qi and consolidating absorption was revealed to be related to the improvement of ATP synthase, the increase of ATP content in vascular endothelial cells, the support of F-acitn and gap junction protein, and the closing of gap junction.
Yang Baofeng, academician of the Chinese Academy of Engineering, who participated in the discussion at the salon, said that only by clarifying the mechanism of Chinese medicine can we give full play to the clinical advantages of Chinese medicine. In the treatment of microvascular exudation, the theory of qi deficiency without fixation and the theory of supplementing qi for fixation do not follow the theory of osmotic pressure and tissue pressure of western medicine. Instead, it works by supplementing the energy of microvessels, maintaining the gap connection of microvessels, inhibiting the exudation of plasma proteins and body fluids, preventing the damage of microvessel barrier, and repairing the microvessel barrier. This also provides a new strategy for the clinical treatment of cardiovascular and cerebrovascular problems.
