Paul Wade,Ph.D。
Paul Wade,Ph.D。
Chief,Epigenetics&Stem Cell Biology Laboratory and Principal Investigator
Tel984-287-4133
传真919-541-0146
已保护
P.O.Box 12233
Mail Drop D4-04
Durham,NC27709
Traci Hall,Ph.D。
Traci Hall,Ph.D。
深度Chief and Principal Investigator
Tel984-287-3556
Fax301-480-3055
已保护
P.O.Box 12233
Mail Drop F3-05
Durham,NC27709

Research Summary

TheEpigenetics and Stem Cell Biology Laboratory investigates fundamental mechanisms bywhich epigenetics-non-genetic modulation and alterations-influences chromatin architecture,transcription and gene expression in normal,cancer and embryonic stem cells and provides insights into biological processes that modulate the effects of environmental exposures.It also focuses on the molecular basis of self-renewal and pluripotency in embryonic stem(ES)cells and induced pluripotecy stem(iPS)cells,as well as gene regulatory pathways using genomic,molecular,biochemical,computational and structural approaches。

inaddition to the cutting edge hypothesis driven research of its investigators the laboratory provides leadership and support to the NIEHS in areas of genomics,epigenomics,mass spectrometry, and bioinformatics analyses.These endeavors build and research strengths established in the prior Laboratory of Molecular Carcinogenesis and extend the scope of the research beyond cancer to examine a broad range of environmental impacts on human health and development。

Scientific Support Staff

Derrick L.Raynor
管理技术
Tel984-287-4006
已保护