ISOLUTE混合型填充剂

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ISOLUTE® Mixed-mode SPE

混合型填料

ISOLUTE混合模式填料列表。

ISOLUTE HCX

ISOLUTE HCX-3

ISOLUTE HCX-5

ISOLUTE HCX-Q

ISOLUTE HAX

ISOLUTE Multimode

ISOLUTE HCX, HCX-3 AND HCX-5

Figure 2: Multiple (hydrophobic and cation exchange) interactions on ISOLUTE HCX, HCX-3 and HCX-5

ISOLUTE HCX (sorbent ref. 902)

Description

Mixed-mode C8 and strong cation exchange functionalized silica. Manufactured using trifunctional silanes. Non end-capped.

Average Particle Size

50μm

Nominal Porosity

60A

Comments

First choice for generic methods for high purity basic drug extracts

Chemistry Data Sheet

  • TN116（PDF 68.5KB）
    ISOLUTE混合模式填充剂从生物样品中提取碱性化合物的一般方法（英文资料）
  • TN125（PDF 67.2KB）
    ISOLUTE HCX混合模式填料的样品预处理（英文资料）
ISOLUTE HCX订购信息

ISOLUTE HCX-3 (sorbent ref. 905)

Description

Mixed-mode C18 and strong cation exchange functionalized silica. Manufactured using trifunctional silanes. Non end-capped.

Average Particle Size

50μm

Nominal Porosity

60A

Comments

Alternative to ISOLUTE HCX where more rententive non-polar sorbent is required for rentention of polar compounds.

Chemistry Data Sheet

  • TN116（PDF 68.5KB）
    ISOLUTE混合模式填充剂从生物样品中提取碱性化合物的一般方法（英文资料）
ISOLUTE HCX-3订单信息

ISOLUTE HCX-5 (sorbent ref. 906)

Description

Mixed-mode C4 and strong cation exchange functionalized silica. Manufactured using trifunctional silanes. Non end-capped.

Average Particle Size

50μm

Nominal Porosity

60A

Comments

Alternative to ISOLUTE HCX, where less retentive non-polar sorbent can provide cleaner extracts.

Chemistry Data Sheet

  • TN116（PDF 68.5KB）
    ISOLUTE混合模式填充剂从生物样品中提取碱性化合物的一般方法（英文资料）
ISOLUTE HCX-5订单信息

ISOLUTE HCX-Q (sorbent ref. 986)

Description

Mixed-mode C8 and weak cation exchange functionalized silica. Manufactured using trifunctional silanes. Non end-capped.

Average Particle Size

50μm

Nominal Porosity

60A

Comments

Generic method for high purity extracts of quaternary amines or strongly basic drugs.

Chemistry Data Sheet

  • TN129（PDF 69.1KB）
    ISOLUTE HCX-Q从生物样品中提取季胺和多碱化合物的一般方法（英文资料）
ISOLUTE HCX-Q订单信息

ISOLUTE HAX (sorbent ref. 903)

Figure 3: Multiple (hydrophobic and anion exchange) interactions on ISOLUTE HAX

Description

Mixed-mode C8 and strong anion exchange functionalized silica. Manufactured using trifunctional silanes. Non end-capped.

Average Particle Size

50μm

Nominal Porosity

60A

Comments

Generic method for high purity acidic drug extracts

Chemistry Data Sheet

ISOLUTE HAX订购信息

ISOLUTE Multimode (sorbent ref. 904)

Description

Mixed-mode column containing both non-polar (C18), strong cation exchange (-SO3-) and strong anion exchange (-NR3+) functional groups.

Average Particle Size

50μm

Nominal Porosity

60A

ISOLUTE多模式订购信息

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