Stem Cell
The medical use of stem cells，cells with the ability to perpetuate themselves through self-renewal and to differentiate intoa particular cell type through differentation，is receiving extensive interest as they might regenerate damaged tissue under the right conditions[1].This unique capacity could serve patients suffering from organ malfunction，cell deficiency，and/or neurodegenerative diseases such asAlzheimer’sand，andParkinson’s直接回填的污水处理厂[2]。
Stem cells are unspecialized cells with an extraordinary ability to self-renew，capable of differentiating into one or more specialized cell types.When called into action following an injury， astem cell self-renews–undergoes cell division and gives rise to one daughter stem cell and one progenitor cell.A progenitor cell is an intermediate cell type forme before it achieves a fully differentiated state.It is regarded as committed to differentiating along a particular cellular delopmental pathwaystem of
Stem cell→Stem cell+Progenitor cell→Differentiated cell
Based on their origin，stem cells are categorized either as embryonic stem cells（ESCs）oras postnatal stem cells/somatic stem cells/adult stem cells（ASCs）。They are characterized as totipotent（can generate all types of cells including germ cells（ESCs），pluripotent（can generate all types of cells except cells of the embryonic membrane），multipotent（can differentiate into more than one mature cell（MSC）），self-renewable pply），and malleable stem cells（MSCs have plasticity and can undergo differentiation。
Among the types of分配，分配are:
- 直连differentiation:specific type of cell in a special niche developed in a multistep unidirectional pathway；
- Transdifferentiation:direct conversion of one cell type to another different cell type；
- Dedifferentiation:unipotent stem cell becoming a multipotent one；
- Cell fusion:stem cell fusing with a somatic cell resulting in another lineage。[3]
Stem cell Products Library
未来convenience，you can order alibraryof all of our Stem cell research related products。Make your personal library by cherry picking products of your interest from our comprehensive list（142products），order all together not to miss any.The libraries will be shipped as10mM solutions（in DMSO，250µLof each selected Axon Ligand™）ona96-well microtiter plate with a clear map of its contents。
Simply download our comprehensive list of epigenetics products below（Microsoft Excel（.xls）），check the products to be included，andreturn your listto order the library of your preference。
The pharmacological tools in this category could interact in any way with the complex cell differentiating processes involved in the transformation of an un-programmed stem cell into its destination cell type.Examples of biological targets of significance in stem cell research are:
[1]Stem cells，cancer，and cancer stem cells.Tannishtha Reya，Sean J.Morrison，Michael F.Clarke，Irving L.Weissman.Nature，Vol414，2001105。
[2]Embryonic stem cells in drug discovery.J.McNeish.Nature Rev.Drug Disc.2004,3,70。
[3]from:R.R.Nadig et al.Stem cell therapy-Hype or hope？A review.J.Conserv.Dent.2009,12131-138。
