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结果byyear

Table representation of search results timeline featuring number of search results per year。

年,年 Number of Results
1796 1个
1799 1个
1800 1个
1802 1个
1804 1个
1808 3
1810 1个
1813 1个
1820 1个
1831 1个
1840 1个
1842 3
1843 1个
1845 2
1847 1个
1848 8个
1849 1个
1850 1个
1852 2
1853 2
1858 3
1859 1个
1860 1个
1862 1个
1864 1个
1865 1个
1867 1个
1869 5
1870 1个
1871 8个
1873 4个
1874 5
1875 2
1876 2
1877 3
1878 5
1879 1个
1880 2
1881 1个
1882 7
1883 2
1884 2
1885 6个
1886 6个
1887 3
1888 5
1889 2
1890 6个
1891 4个
1892 5
1893 4个
1894 1个
1895 2
1896 6个
1897 10
1898 4个
1899 5
1900 3
1901 7
1902 6个
1903 4个
1904 3
1905 3
1906 7
1907 5
1908 3
1909 2
1910 4个
1911 5
1912 4个
1913 9
1914 11
1915 12
1916 6个
1917 9
1918 14
1919 9
1920 9
1921 15
1922 16
1923 11
1924 6个
1925 5
1926 18
1927 14
1928 10
1929 27
1930 25
1931 第二十四节:
1932 33
1933 41
1934 45
1935 38
1936 41
1937 第二十四节:
1938 22
1939 21
1940 第十七节:
1941 第二十四节:
1942 18
1943 9
1944 23
1945 60
1946 118
1947 325
1948 399
1949 295
1950 676
1951 821
1952 827
1953 712
1954 897
1955 813
1956 738
1957 758
1958 726
1959 601
1960 661
1961 638
1962 715
1963 1191
1964 1800
1965 1619
1966 1613
1967 1882
1968 2223
1969 2758
1970 3177
1971 3517
1972 3422
1973 3532
1974 4009
1975 7744
1976 7855
1977 7488
1978 7661
1979 8520
1980 8885
1981 9511
1982 10338
1983 11876
1984 12769
1985 13287
1986 13655
1987 14974
1988 16751
1989 19219
1990 20453
1991 20248
1992 20151
1993 21017
1994 21210
1995 21739
1996 23279
1997 24112
1998 25216
1999 27030
2000 29722
2001 31295
2002 33241
2003 35944
2004 37754
2005 41393
2006 44383
2007年 47394
2008年 49843
2009年 51931
2010 56540
2011 62285
2012 68208
2013 72395
2014 80817
2015 86098
2016 87890
2017 91078
2018 99979
2019 107494
2020 121378
2021 132721
2022 133946
2023 128839
2024 62048
2025 2

文本可用性

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发布日期

搜索结果

2015500results

结果byyear

文件应用程序:Clear all
第1页
热塑性动态GProteins During GPCR-Mediated Activation。
Ahn D,Chung KY。 Ahn D,et al。 Subcell Biochem.2022;99:271-284.doi:10.10007/978-3-031-00793-4_8。 Subcell Biochem.2022。 PMID:36151379 Review。
HeterotrimericGproteins(Gproteins)are essential cellular signaling proteins that mediate extracellular signals to achieve various cellular functions。G-protein-coupled receptors(GPCRs)are the major guanine nucleotide exchange factors(GEFs)that induce…
HeterotrimericGproteins(Gproteins)are essential cellular signaling proteins that mediate extracellular signals to achieve…
Cryo-EM structures of GPCRs coupled toG(s),G(i)andG(o)。
García-Nafría J,Tate CG。 García-Nafría J,et al。 Mol Cell Endocrinol.2019May15;488:1-13.doi:10.1016/j.mce.2019.02.006.Epub2019Mar28。 Mol Cell Endocrinol.2019。 PMID:30930094 Review。
GPCRs coupled to either heterotrimericGproteins(G(s),G(i)orG(o)或mini-Gproteins(mini-G(s)or mini-G(o)by single-particle cryo-EM and X-ray crystallography,respectively.…In additio…
GPCRs coupled to either heterotrimericGproteins(G(s),G(i)orG(o)or min…
结构一致性G工程用温度计G保护和smallGprotein。
Luo M,Han Z,Huang G,Li R,Liu Y,Lu J,Liu L,Miao R。 Luo M,et al。 Plant Signal Behav.2022 Dec31;17(1):2024405。doi:10.1080/155923.2021.2024405.Epub2022Feb8。 Plant Signal Behav.2022。 PMID:35135414 Free PMC article。 Review。
Based on the structural characteristics,Gproteins can be divided into heterotrimericGproteins,smallGproteins and multiple unique unconventionalGproteins.…In this review,we compared the structural characteristics of theGdomain in r…
Based on the structural characteristics,Gproteins can be divided into heterotrimericGproteins,smallGproteins and…
Nanoparticles targeting HLA-Gfor gene therapy in cancer。
Zidi I,Ben Amor N。 Zidi I,et al。 Med Oncol.2012Jun;29(2):1384-90。doi:10.1007/s12032-011-9942-8.Epub2011Apr17。 Med Oncol.2012。 PMID:21499927 Review。
cancer cells are aided by immune-tolerant functions of HLA-Gto escape the immune surveillance.In general,cancer cells can express membranous HLA-G单击功能区上,secrete soluble HLA-G,产品HLA-Gpositive exosomes,and can be subjected to proteolytic cleavage…
cancer cells are aided by immune-tolerant functions of HLA-Gto escape the immune surveillance.In general,cancer cells can express…
接收到的已编码到heterotrimericGproteins of the G12family。
Riobo NA,Manning DR。 Riobo NA,et al。 Trends Pharmacol Sci.2005 Mar;26(3):146-54。doi:10.1016/j.tips.2005.01.07。 Trends Pharmacol Sci.2005。 PMID:15749160 Review。
uch regarding the engagement of theG(12)family of heterotrimericGproteins(G(12)andG(13)by agonist-activated receptors remains unclear。。。Furthermore,receptors that couple toG(12)andG(13)invariable couple to additionalG
uch regarding the engagement of theG(12)family of heterotrimericGproteins(G(12)andG(13)by agonist-acti…
Structural insights into adhesion GPCR ADGRL3 activation andG(q),G(s),G(i),andG(12)coupling。
Qian Y,Ma Z,Liu C,Li X,Zhu X,Wang N,Xu Z,Xia R,Liang J,Duan Y,Yin H,Xiong Y,Zhang A,Guo C,Chen Z,Huang Z,He Y。 Qian Y,et al。 Mol Cell.2022 Nov17;82(22):4340-4352.e6。doi:10.1016/j.molcel.2022.10.09.Epub2022Oct28。 Mol Cell.2022。 PMID:36309016 Free article。
Here,we present cryoelectron microscopy(cryo-EM)structures of ADGRL3in complex withG(q),G(s),G(i),andG(12)。The structures reveal unique ligand-engaging mode,distinctive activation conformation,and key mechanism of aGPCR activation.The str…
Here,we present cryoelectron microscopy(cryo-EM)structures of ADGRL3in complex withG(q),G(s),G(i),andG(…
PenicillinG
Friend DG。 Friend DG。 Clin Pharmacol Ther.1966May-Jun;7(3):421-4。doi:10.1002/cpt196673421。 Clin Pharmacol Ther.1966。 PMID:5937005 No abstract available。
单击功能区上Gproteins:privileged transducers of 7-transmembrane spanning receptors]。
Hanson J。 Hanson J。 Biol Aujourdhui.2021;215(3-4):95-106。doi:10.01051/jbio/2021011.Epub2022Mar11。 Biol Aujourdhui.2021。 PMID:35275054 French。
In addition,they constitute 30%of the targets of currently marketed drugs and remain an important reservoir for new innovative therapies.Their main effectors are heterotrimericGproteins.These are composed of 3subunits,alpha,beta and gamma,which,upon coupling wit…
In addition,they constitute 30%of the targets of currently marketed drugs and remain an important reservoir for new innovative therapies…
Xanthine and 8-oxoguanine inG-quadruplexes:formation of aGG.X.O tetrad。
Cheong VV,Heddi B,Lech CJ,Phan AT。 Cheong VV,et al。 Nucleic Acids Res.2015Dec2;43(21):10506-14。doi:10.1093/nar/gkv826.Epub2015Sep22。 Nucleic Acids Res.2015。 PMID:26400177 Free PMC article。
G已从-quadruplexes are four-stranded structures builtG-tetrads(GGGG),which are planar cyclical assemblies of four guanine bases interacting through Hoogsteen hydrogen bonds.…We show that a proper arrangement of O and Xb
G已从-quadruplexes are four-stranded structures builtG-tetrads(GGGG),which are plan
单核monomers,dimers and HLA-G-expressing extracellular vesicles:the three dimensions of structural complexity to use HLA-Gas a clinical biomarker。
Nardi Fda S,König L,Wagner B,Giebel B,Santos Manvailer LF,Rebmann V。 Nardi Fda S,et al。 HLA.2016Sep;88(3):77-86。doi:10.11111/tan.12844.Epub2016Jul21。 HLA.2016。 PMID:27440734 Review。
The HLA-Gmolecule belongs to the family of nonclassical human leukocyte antigen(HLA)class I。。。可熔式过热器G(sHLA-G)are detectable in various body fluids。Cellular activation and pathological processes are associated with an aberrant or a neo-e…
The HLA-Gmolecule belongs to the family of nonclassical human leukocyte antigen(HLA)class I。。。可熔式过热器G(sHL…
2015500results
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