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Review
.2013 Jan;57(1):165-86.
doi: 10.1002/mnfr.201100764. Epub 2012 Oct 10.

Masked mycotoxins: a review

Franz Berthiller 1, Colin Crews, Chiara Dall'Asta, Sarah De Saeger, Geert Haesaert, Petr Karlovsky, Isabelle P Oswald, Walburga Seefelder, Gerrit Speijers, Joerg Stroka
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Free PMC article
Review

Masked mycotoxins: a review

Franz Berthiller et al. Mol Nutr Food Res. 2013 Jan.
Free PMC article

Abstract

The aim of this review is to give a comprehensive overview of the current knowledge on plant metabolites of mycotoxins, also called masked mycotoxins. Mycotoxins are secondary fungal metabolites, toxic to human and animals. Toxigenic fungi often grow on edible plants, thus contaminating food and feed. Plants, as living organisms, can alter the chemical structure of mycotoxins as part of their defence against xenobiotics. The extractable conjugated or non-extractable bound mycotoxins formed remain present in the plant tissue but are currently neither routinely screened for in food nor regulated by legislation, thus they may be considered masked. Fusarium mycotoxins (deoxynivalenol, zearalenone, fumonisins, nivalenol, fusarenon-X, T-2 toxin, HT-2 toxin, fusaric acid) are prone to metabolisation or binding by plants, but transformation of other mycotoxins by plants (ochratoxin A, patulin, destruxins) has also been described. Toxicological data are scarce, but several studies highlight the potential threat to consumer safety from these substances. In particular, the possible hydrolysis of masked mycotoxins back to their toxic parents during mammalian digestion raises concerns. Dedicated chapters of this article address plant metabolism as well as the occurrence of masked mycotoxins in food, analytical aspects for their determination, toxicology and their impact on stakeholders.

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Figure 1
Figure 1
Structurally elucidated masked mycotoxins.
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References

    1. Lawley L, Curtis L, Davis J. Royal Society of Chemistry. Cambridge, UK: RSC Publishing; 2008. The Food Safety Hazard Guidebook.
    1. Riemann HP, Cliver DO. Foodborne Infections and Intoxications. Amsterdam, NL: Elsevier Academic Press; 2006.
    1. Murphy PA, Hendrich S, Landgren C, Bryant CM. Food mycotoxins: an update. J. Food Sci. 2006;71:51–65.
    1. Mattsson JL. Mixtures in the real world: the importance of plant self-defense toxicants, mycotoxins, and the human diet. Toxicol. Appl. Pharmacol. 2007;223:125–132.-PubMed
    1. Van Egmond HP, Speijers GJA. In: International Food Safety Handbook. van der Heijden K, Younes M, Fishbein L, Miller S, editors. New York: Marcel Dekker; 1999. pp. 341–356.

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