{“id”：“https://openalex.org/W2168492379“，”doi“：”https://doi.org/10.1093/bioinformatics/btm152生物信息学“，”title“：“AutoCSA，一种用于癌症基因组中高通量DNA序列变异检测的算法”，“display_name”：“AutoCS，一种在癌症基因组中进行高通量DNA顺序变异检测的方法”，“publication_year”：2007，“publitation_date”：“2007-05-07”，“ids”：{“openalex”：“https://openalex.org/W2168492379“，”doi“：”https://doi.org/10.1093/bioinformatics/btm152“，”mag“：”2168492379“，”pmid“：”https://pubmed.ncbi.nlm.nih.gov/17485433“，”pmcid“：”https://www.ncbi.nlm.nih.gov/pmc/articles/5947781“}，”language“：”en“，”primary_location“：{”is_oa“：true，”landing_page_url“：”https://doi.org/10.1093/bioinformatics/btm152，“pdf_url”：https://academic.oup.com/bioinformatics/article-pdf/23/13/1689/23704089/btm152.pdf，“源”：{“id”：https://openalex.org/S52395412“，”display_name“：”生物信息学“，”issn_l“：”1367-4803“，”isn“：[”1367-483“，“1367-4811”]，”is_oa“：true，”is_ in_doaj“：true，”is_core“：true，”host_organization“：”https://openalex.org/P4310311648“，”“host_organization_name”：“牛津大学出版社”，“host_ordanization_lineage”：[“https://openalex.org/P4310311647","https://openalex.org/P4310311648“]，”host_organization_lineage_names“：[”牛津大学“，”牛津大学出版社“]，“type”：“journal”}，“license”：“cc-by-nc”，“licence_id”：“https://openalex.org/licenses/cc-by-nc“，”version“：”publishedVersion“，”is_accepted“：true，”is_published“：true}，”type“：”article“，”type_crossref“：“journal-article”，”indexed_in“：[”crossref“，”publimed“]，”open_access“：{”is_oa“：true，”oa_status“：”hybrid“，”oa_url“：”https://academic.oup.com/bioinformatics/article-pdf/23/13/1689/23704089/btm152.pdf“，”any_repository_has_fulltext“：true}，”authorships“：[{”author_position“：”第一“，”作者“：{”id“：”https://openalex.org/A5051394526“，”display_name“：”Ed Dicks“，”orcid“：”https://orcid.org/0000-0002-0617-0401}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”E.Dicks“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，惠康信托桑格研究所，基因组园区，剑桥，剑桥，CB10 1SA和2NGRL（威塞克斯），索尔兹伯里地区医院，索尔兹伯里，SP2 8BJ，英国”，“机构ID”：[”https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5029096739“，”display_name“：”Joshua M.Stuart“，”orcid“：”https://orcid.org/0000-0002-2171-565X}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”威康桑格研究所“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”J.W.Teague“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5011609796“，”display_name“：”Philip J.Stephens“，”orcid“：null}，”institutions“：[{”id“：”https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”P.Stephens“，”raw _ affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliation”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5011152441“，”display_name“：”Keiran Raine“，”orcid“：”https://orcid.org/0000-0002-5634-1539}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”网址：https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”K.Raine“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5062352940“，”display_name“：”Andrew Yates“，”orcid“：”https://orcid.org/0000-0002-8886-4772}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”A.Yates“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5060966201“，”display_name“：”Michael A.Morris“，”orcid“：”https://orcid.org/0000-0002-9660-505X}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]｝]，”国家“：[”GB“]，”is_correresponsing“：false，”raw_author_name“：”C.Mattocks“，”raw_affiation_string“：[”1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK and 2NGRL（Wessex），Salisbury District Hospital，Salisbury，SP2 8BJ，UK“]，”附属机构“：[｛”raw_affiation_string“：”1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5045328655“，”display_name“：”Patrick Tarpey“，”orcid“：”https://orcid.org/0000-0002-2042-4543}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”P.Tarpey“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5007140000“，”display_name“：”Adam P.Butler“，”orcid“：null}，”institutions“：[{”id“：”https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”A.Butler“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5054740288“，”display_name“：”Andrew Menzies“，”orcid“：”https://orcid.org/0000-0003-0343-5758}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”A.Menzies“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5031861795“，”display_name“：”David Richardson“，”orcid“：”https://orcid.org/0000-0003-0247-9118}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”D.Richardson“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5082056915“，”display_name“：”Andy Jenkinson“，”orcid“：”https://orcid.org/0000-0002-0703-6984}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”A.Jenkinson“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5075956178“，”display_name“：”Helen Davies“，”orcid“：”https://orcid.org/0000-0001-6381-3664}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”H.Davies“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5002960171“，”display_name“：”Sarah Edkins“，”orcid“：”https://orcid.org/0000-0003-0717-1972}，“机构”：[{“id”：https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}，{”id“：”https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”S.Edkins“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2802476451","https://openalex.org/I2799594651“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5027732352“，”display_name“：”Simon Forbes“，”orcid“：null}，”institutions“：[{”id“：”https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”S.Forbes“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5002994007“，”display_name“：”克里斯蒂安·格雷“，”兽人“：”https://orcid.org/0000-0002-7035-7107}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”country_code“：”GB“，”type“：”healthcare“，”沿袭“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”K.Gray“，”raw _affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation _string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5010958185“，”display_name“：”Chris Greenman“，”orcid“：”https://orcid.org/0000-0002-4338-8012}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]｝]，”国家“：[”GB“]，”is_correresponsing“：false，”raw_author_name“：”C.Greenman“，”raw_affiation_string“：[”1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK and 2NGRL（Wessex），Salisbury District Hospital，Salisbury，SP2 8BJ，UK“]，”附属机构“：[｛”raw_affiation_string“：”1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5053211827“，”display_name“：”Rebecca Shepherd“，”orcid“：”https://orcid.org/0000-0002-8888-305X}，“机构”：[{“id”：https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}，{”id“：”https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”R.Shepherd“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2802476451","https://openalex.org/I2799594651“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5058103562“，”display_name“：”Michael R.Stratton“，”orcid“：”https://orcid.org/0000-0001-6035-153X}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”M.R.Stratton“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}，{”author_position“：”middle“，”author“：{”id“：”https://openalex.org/A5067102201“，”display_name“：”P.Andrew Futreal“，”orcid“：”https://orcid.org/0000-0001-8663-2671}，“机构”：[{“id”：https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”威康桑格研究所“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”P.A.Futreal“，”raw _ afiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliations”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]｝]｝，｛”author_position“：”last“，”author“：｛”id“：”https://openalex.org/A5022949064“，”display_name“：”Richard Wooster“，”orcid“：null}，”institutions“：[{”id“：”https://openalex.org/I2799594651“，”display_name“：”索尔兹伯里区医院“，”ror“：”https://ror.org/05bx2yj81“，”“country_code”“：”GB“，”type“：”healthcare“，”seriance“：[”https://openalex.org/I2799594651","https://openalex.org/I79209787“]}，{”id“：”https://openalex.org/I2802476451“，”display_name“：”Wellcome Sanger Institute“，”ror“：”https://ror.org/05cy4wa09“，”“country_code”“：”GB“，”type“：”非营利性“，”世系“：[”https://openalex.org/I2802476451","https://openalex.org/I87048295“]}]，”国家“：[”GB“]，”is_corresponding“：false，”raw_author_name“：”R.Wooster“，”raw _ affiliation_strings“：[“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Salisbery，SP2 8BJ，UK”]，“affiliation”：[{“raw_affiliation_string”：“1癌症基因组项目，Wellcome Trust Sanger Institute，Genome Campus，Hinxton，Cambridge，CB10 1SA，UK和2NGRL（Wessex），Salisbury District Hospital，Solisbury，SP2 8BJ，UK“，“institution_ids”：[“https://openalex.org/I2799594651","https://openalex.org/I2802476451“]}]}]，”countries_distinct_count“：1，”institutions_disting_count”：2，”corresponding_author_ids“：[]，”corresponding_institution_ids”：[]、“apc_list”：{“value”：3618，”currency“：”USD“，”value_USD“：3618、”provenance“：”doaj“}，”apc_payed“：{”value“：36十八，”curvency“USD”：36十八、“provenance”：“doaj”“}，”fwci“：1.106，”has_fulltext“：true，”fulltext_origin“：”pdf”，“cited_by_count”：16，“citation_normalized_p百分位”：｛“value”：0.603828，“is_in_top_1_percent”：false，“is_in_top_1_percent”：false｝，“cited_by_percentle_year”：｛“min”：86，“max”：87｝，“biblio”：｛“volume”：“23”，“issue”：“13”，“first_page”：“1689”，“last_page”：“1691”｝，“is_retracted”：false，“is_paratext”：false，“primary_topic“：｛”id“：”https://openalex.org/T10015“，”display_name“：”RNA测序数据分析“，”score“：0.9982，”subfield“：{”id“：”https://openalex.org/subfields/1312“，”display_name“：”分子生物学“}，”字段“：{”id“：”https://openalex.org/fields/13“，”“display_name”：“生物化学、遗传学和分子生物学”}，“域”：{“id”：“https://openalex.org/domains/1“，”display_name“：”生命科学“}}，”主题“：[{”id“：”https://openalex.org/T10015“，”display_name“：”RNA测序数据分析“，”score“：0.9982，”subfield“：{”id“：”https://openalex.org/subfields/1312“，”display_name“：”分子生物学“}，”字段“：{”id“：”https://openalex.org/fields/13“，”“display_name”：“生物化学、遗传学和分子生物学”}，“域”：{“id”：“https://openalex.org/domains/1“，”display_name“：”生命科学“}}，{”id“：”https://openalex.org/T11642“，”“display_name”：“遗传变异解释标准和指南”，“score”：0.9982，“subfield”：{“id”：“https://openalex.org/subfields/1311“，”display_name“：”Genetics“}，”field“：{”id“：”https://openalex.org/fields/13“，”“display_name”：“生物化学、遗传学和分子生物学”}，“域”：{“id”：“https://openalex.org/domains/1“，”display_name“：”生命科学“}}，{”id“：”https://openalex.org/T11287“，”“display_name”：“癌症基因组景观和突变特征”，“score”：0.9947，“subfield”：{“id”：“https://openalex.org/subfields/1306“，”“display_name”“：”癌症研究“}，”字段“：{”id“：”https://openalex.org/fields/13“，”“display_name”：“生物化学、遗传学和分子生物学”}，“域”：{“id”：“https://openalex.org/domains/1“，”display_name“：”生命科学“}}]，”关键词“：[{”id“：”https://openalex.org/keywords/sanger-sequencing（https://openalex.org/keywords/sanger-sequencing）“，”display_name“：”Sanger sequencing“，”score“：0.8797939｝，｛”id“：”https://openalex.org/关键词/癌症经济学“，”display_name“：”癌症基因组学“，”score“：0.554704}，{”id“：”https://openalex.org/keywords/genome-annotation网站“，”display_name“：”基因组注释“，”score“：0.536918}，{”id“：”https://openalex.org/keywords/exome-sequencing网站“，”display_name“：”Exome Sequenting“，”score“：0.531548}，{”id“：”https://openalex.org/keywords/sequence-alignment网站“，”display_name“：”sequence alignment“，”score“：0.50646}，{”id“：”https://openalex.org/keywords/sequence-variation网站“，”display_name“：”sequence variation“，”score“：0.503771}]，”concepts“：[{”id“：”https://openalex.org/C76818968，“wikidata”：https://www.wikidata.org/wiki/Q181940“，”display_name“：”Sanger测序“，”level“：4，”score“：0.8797939}，{”id“：”https://openalex.org/C51679486，“wikidata”：https://www.wikidata.org/wiki/Q380546“，”“display_name”“：”DNA测序“，”级别“：3，”分数“：0.6522228}，{”id“：”https://openalex.org/C86803240，“wikidata”：https://www.wikidata.org/wiki/Q420“，”display_name“：”生物学“，”等级“：0，”分数“：0.55917156}，{”id“：”https://openalex.org/C70721500，“wikidata”：https://www.wikidata.org/wiki/Q177005“，”display_name“：”计算生物学“，”level“：1，”score“：0.5516626}，{”id“：”https://openalex.org/C54355233，“wikidata”：https://www.wikidata.org/wiki/Q7162“，”display_name“：”Genetics“，”level“：1，”score“：0.5134657}，{”id“：”https://openalex.org/C141231307，“wikidata”：https://www.wikidata.org/wiki/Q7020“，”display_name“：”基因组“，”level“：3，”score“：0.5017934}，{”id“：”https://openalex.org/C121608353，“wikidata”：https://www.wikidata.org/wiki/Q12078“，”display_name“：”Cancer“，”level“：2，”score“：0.4931404}，{”id“：”https://openalex.org/C157764524，“wikidata”：https://www.wikidata.org/wiki/Q1383412“，”display_name“：”吞吐量“，”级别“：3，”分数“：0.47303885}，{”id“：”https://openalex.org/C134305767，“wikidata”：https://www.wikidata.org/wiki/Q725508“，”“display_name”“：”体细胞“，”级别“：3，”分数“：0.46366623}，{”id“：”https://openalex.org/C501734568，“wikidata”：https://www.wikidata.org/wiki/Q42918“，”display_name“：”突变“，”等级“：3，”分数“：0.45317984}，{”id“：”https://openalex.org/C552990157，“wikidata”：https://www.wikidata.org/wiki/Q7430“，”display_name“：”DNA“，”level“：2，”score“：0.4348843}，{”id“：”https://openalex.org/C104317684，“wikidata”：https://www.wikidata.org/wiki/Q7187“，”display_name“：”Gene“，”level“：2，”score“：0.2645613}，{”id“：”https://openalex.org/C41008148，“wikidata”：https://www.wikidata.org/wiki/Q21198“，”display_name“：”计算机科学“，”level“：0，”score“：0.21306154}，{”id“：”https://openalex.org/C76155785，“wikidata”：https://www.wikidata.org/wiki/Q418“，”display_name“：”Telecommunications“，”level“：1，”score“：0.0}，{”id“：”https://openalex.org/C555944384，“wikidata”：https://www.wikidata.org/wiki/Q249“，”display_name“：”Wireless“，”level“：2，”score“：0.0}]，”mesh“：[{”descriptor_ui“：”D002874“，”描述符名称“：”染色体映射“，”qualifier_ui”：“Q000379”，“qualifier _name”：“methods”，“is_major_topic”：true}，{”描述符名称or_topic“：true}，{”descriptor_ui“：”D004273“，”descriptor_name“：”DNA，肿瘤“，”限定符_ui”：“Q000235”，“限定符_name”：“遗传学”，“is_major_topic”：真}，{“descriptor_ ui”:“D005820”，“descriptor _name”:“遗传测试”，“qualifier_ui（限定符_ ui）：“Q000 379”，“qualifier_name（限定符名称）”：“methods”，“is _major _topic（限定符名）”：真{“descriptor_ui”：“D009369”，“描述符_name（名称）：“肿瘤”，“限定符ui（_U）”：“Q000175”，“qualifier_name”：“诊断”，“is_major_topic”：true｝，｛“descriptor_ui”：“D000465”，“descriptor_name”：“算法”，“qualifier_ui”：“”，“qualifier_name”：null，“is_major_topic”：false｝，｛“descriptor_ui”：“D001483”，“descriptor_name”：“基本序列”，“qualifier_ui”：“”，“qualifier_name”：null，“is_major_topic”：false｝，｛“descriptor_ui”：“D020022”，“descriptor_name“：“疾病的遗传易感性”，“qualifier_ui”：“Q000235”，“qualifier_name”：“genetics”，“is_major_topic”：false｝，｛“descriptor_ui”：“D014644”，“descriptor_name”：“Genetic Variation”，“qualifier_ui”：“Q000235”，“qualifier_name”：“genetics”，“is_major_topic”：false｝，｛“descriptor_ui”：“D006801”，“descriptor_name”：“Humans”，“qualifier_ui”：“，”限定符名称“：null，”is_major_topic“：false}，”描述符名称“：”D008969“，”描述符姓名“：”分子序列数据“，”限定符_ui“：”“，”qualifier_name“：nul，”is_ major_topic“:false{，”descriptor_ui”：“D012984”，“描述符名称”：“软件”，”限定词_ui：true，“登录页面url“：”https://doi.org/10.1093/bioinformatics/btm152，“pdf_url”：https://academic.oup.com/bioinformatics/article-pdf/23/13/1689/23704089/btm152.pdf，“源”：{“id”：https://openalex.org/S52395412“，”display_name“：”生物信息学“，”issn_l“：”1367-4803“，”isn“：[”1367-483“，“1367-4811”]，”is_oa“：true，”is_ in_doaj“：true，”is_core“：true，”host_organization“：”https://openalex.org/P4310311648“，”“host_organization_name”：“牛津大学出版社”，“host_ordanization_lineage”：[“https://openalex.org/P4310311647","https://openalex.org/P4310311648“]，”host_organization_lineage_names“：[”牛津大学“，”牛津大学出版社“]，“type”：“journal”}，“license”：“cc-by-nc”，“licence_id”：“https://openalex.org/licenses/cc-by-nc“，”版本“：”已发布版本“，”is_accepted“：true，”is_published“：true｝，｛”is_oa“：true，”landing_page_url“：”https://europepmc.org/articles/pmc5947781，“pdf_url”：https://europepmc.org/articles/pmc5947781？pdf=render，“源”：{“id”：https://openalex.org/S4306400806“，”display_name“：”Europe PMC（PubMed Central）“，”issn_l“：null，”issn“：null，”is_oa“：true，”is_ in_doaj“：false，”is_core“：false，”host_organization“：”https://openalex.org/I1303153112“，”“host_organization_name”：“欧洲生物信息学研究所”，“host_organization_lineage”：[“https://openalex.org/I1303153112“]，”host_organization_lineage_names“：[”欧洲生物信息学研究所“]，“type”：“repository”}，“license”：“cc-by-nc”，“licence_id”：“https://openalex.org/licenses/cc-by-nc“，”version“：”acceptedVersion“，”is_accepted“：true，”is_published“：false}，{”is_oa“：true，”landing_page_url“：”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947781“，”pdf_url“：空，”源“：{”id“：”https://openalex.org/S2764455111“，”display_name“：”PubMed Central“，”issn_l“：null，”issn“：null，”is_oa“：true，”is_ in_doaj“：false，”is_core“：false，”host_organization“：”https://openalex.org/I1299303238“，”“host_organization_name”：“美国国立卫生研究院”，“host_ordanization_lineage”：[“https://openalex.org/I1299303238“]，”host_organization_lineage_names“：[”National Institutes of Health“]，“type”：“repository”}，“license”：null，“licence_id”：null，“version”：“acceptedVersion”，“is_accepted”：true，“is_published”：false}，{“is_oa”：false，“landing_page_url”：“https://pubmed.ncbi.nlm.nih.gov/17485433“，”pdf_url“：空，”源“：{”id“：”https://openalex.org/S4306525036“，”display_name“：”PubMed“，”issn_l“：null，”issn“：null，”is_oa“：false，”is_ in_doaj“：false，”is_core“：false，”host_organization“：”https://openalex.org/I1299303238“，”“host_organization_name”：“美国国立卫生研究院”，“host_ordanization_lineage”：[“https://openalex.org/I1299303238“]，”host_organization_lineage_names“：[”National Institutes of Health“]，“type”：“repository”}，“license”：null，“licence_id”：null，“version”：null，“is_accepted”：false，“is_published”：false}]，“best_oa_location”：{“is_oa”：true，“landing_page_url”：“https://doi.org/10.1093/bioinformatics/btm152，“pdf_url”：https://academic.oup.com/bioinformatics/article-pdf/23/13/1689/23704089/btm152.pdf，“源”：{“id”：https://openalex.org/S52395412“，”display_name“：”生物信息学“，”issn_l“：”1367-4803“，”isn“：[”1367-483“，“1367-4811”]，”is_oa“：true，”is_ in_doaj“：true，”is_core“：true，”host_organization“：”https://openalex.org/P4310311648“，”“host_organization_name”：“牛津大学出版社”，“host_ordanization_lineage”：[“https://openalex.org/P4310311647","https://openalex.org/P4310311648“]，”host_organization_lineage_names“：[”牛津大学“，”牛津大学出版社“]，“type”：“journal”}，“license”：“cc-by-nc”，“licence_id”：“https://openalex.org/licenses/cc-by-nc“，”version“：”publishedVersion“，”is_accepted“：true，”is_published“：true}，”sustainable_development_goals“：[]，”grants“：[]，”datasets“：]，”versions“：[https://openalex.org/W1971307410","https://openalex.org/W2023647180","https://openalex.org/W2044586667","https://openalex.org/W2074929099","https://openalex.org/W2083232477","https://openalex.org/W2137503836“]，”related_works“：[”https://openalex.org/W3034729068","https://openalex.org/W3024335473","https://openalex.org/W3024306633","https://openalex.org/W3024168541","https://openalex.org/W2974124152网址","https://openalex.org/W2904387645","https://openalex.org/W2464313322","https://openalex.org/W2049205612","https://openalex.org/W2025457832","https://openalex.org/W138482212“]，”abstract_inverted_index“：{”abstract“：[0]，”The“：[1]，”underming“：[2]，”of“：[3,19,65]，”大规模“：[4]，”DNA“：[5]，”测序“：[6]，”screens“：[7]，”for“：[8,21,60]，”social“：[9]，”variants“：[10,34]，”in“：[11,36]，”human“：[12]，”cancers“：[13,38]，”requiresents“：[14]，“accurate”：[15]，“and”：[16,29,42]，“rapid”：[17]，“processing”：[18]，“trace”：[20]，“variants”：[22]，“由于”：[23]，“到”：[24,44]，“他们的”：[25]，“经常”：[26,40]，“非整倍体”：[27]，“性质”：[28]，“混合”：[30]，“正常”：[31]，“组织”：[32]，“杂合子”：[33]，“发现”：[35]，“初级”：[37]，“是”：[39]，“细微”：[41]，“困难”：[43]，“检测”：[45]，“至”：[46]，“地址”：[47]，“这些”：[48]，“问题”：[49]，“我们”：[50]，“有”：[51]，“发达”：[52]，“a”：[53]，“突变”：[54]，“检测”：[55]，“算法”：[56]，“AutoCSA”：[57]，“具体”：[58]，“优化”：[59]，“the”：[61]，“high”：[62]，“吞吐量”：[63]，“筛查”：[64]，“癌症”：[66]，“样本。”：[67]，“可用性：”：[68]，“http://www.sanger.ac.uk/genetics/CGP/Software/AutoCSA。“：[69]，”联系人：“：[70]，”mrs@sanger.ac.uk“：[71]}，”cited_by_api_url“：”https://api.openalex.org/works？filter=cites:W2168492379“，”counts_by_year“：[{”年份“：2023，”cited_by_count“：1}，{”年度“：2016，”cited_by_count”：1}，{“年份”：2013，”citecd_by_count“：1}]，”updated_date“：”2024-09-13T11:26:24.883960“，”created_dates“：”2016-06-24“}”